About
The department of Pharmaceutics consists of faculty members who conduct research in a variety of areas of Pharmaceutical science. Studies include the improvement of dissolution character of the drugs. Developing modified drug delivery systems, novel drug delivery includes micro-particles, nano-particles, niosomes, transdermal drug delivery systems, mouth dissolving films are the fields of research in the department. Various statistical software were used during development of formulation and optimization. ANOVA, Response surface methodology etc., were applied in the development of formulations. The department is the blend of experienced and young energetic researchers who are actively involved in research and conducting conferences.

Faculty

Infrastructure

Equipments available in our Laboratories

1. Abbe’s refractometer
2. Acto Photometer
3. Ampule sealing apparatus
4. Analgesiometer
5. Andreason pipette
6. Auto Analyzer
7. Auto clave
8. Ball mill
9. Buchner filtration apparatus
10. Bulk density apparatus
11. Capsule Counter Equipment
12. Capsule Filling Machine
13. China dish
14. Clarity testing apparatus
15. Coating equipment
16. Coating Pan
17. Colorimeter
18. Column chromatography
19. Convulsiometer
20. Cookes Pole Climbing Apparatus
21. CST apparatus
22. Desiccators
23. Digital balances
24. Digital electronic balance
25. Digital pH meter
26. Disintegration apparaturs
27. Disintegration test apparatus
28. Dispensing balances
29. Dissolution apparaturs
30. Dissolution testing apparatus
31. Double beam uv visible spectrophotometer
32. Double cone blender
33. Eddys Hot Plate
34. Evaluated  y maze
35. Evaluated plus maze
36. Fourier Transform Infra Red Spectrophotometer
37. Franz diffusion cell
38. Friabilator
39. Friability Apparaturs
40. FTIR
41. Gel Electrophoresis
42. Hardness tester
43. Hardness tester – Pfizer, Monsanto type
44. High Performance Liquid Chromatography
45. Homoginizer
46. Hot Air Oven
47. Hot plate
48. Iron, Brass rods for heat transfer coefficient lab
49. Lipstick moulds
50. Magnetic Stirrer
51. Melting point apparatus
52. Metabolic Cage
53. Microscopes
54. Mortars and pestles
55. Ointment crimping machine
56. Ointment filling machine
57. Ointment slabs and spatula
58. Ostwald’s viscometer
59. Percolators
60. pH meter
61. Plethysmometer
62. Polarimeter
63. Propeller type mechanical agitator
64. Rotary Evaporator
65. Rotary Shaker
66. Seive shaker with set of sieves as per IP
67. Sieves set
68. Single Pan Balance
69. Sling Psychrometers for humidity experiment
70. Stability chamber
71. Stage and eyepiece micrometer
72. Stalagmometer
73. Student organ bath
74. Suppository moulds
75. Tablet punching machine
76. Thermometers
77. Thin layer chromatography
78. Tray dryer
79. UV –Visible spectrophotometer
80. Vaccum pump
81. Vertex
82. Viscometer / Rheometer
83. Water bath

Conferences/Seminars Conducted

2011
National Seminar – PHARMA TRANSPIRE 2011"Emerging novel trends in Drug Delivery Systems"

2013
National Seminar – PHARMA APOTHEOSIS 2013"Nanotherapeutics& Design of Experiments(DOE)"

2014
International Conference – PHARMA TRANSPIRE 2014"Advances in Biopolymer drug delivery systems"

1. 06-02-2010, Mr. K.Mahesh, Jr. Scientist, DRL, Hyderabad, A Seminar on "Novel Drug Delivery System" Faculty and Students.
2. 27-04-2014, Dr.RajkumarMalayandi, Dr.Reddy’s Laboratories, Hyderabad, IVRT of topical and transdermal drug products, Faculty and students.

CESCOP – Department of Pharmaceutics equipped with state of the art facilities and upgraded regularly.

The following were some of the major and recently procured equipments.

· Sophisticated Central Instrumentation Laboratory
· 10 Punch Rotary Tablet Machine.
· Tablet Coating Machine.
· Humidity Controlled Stability Chamber.
· Probe Sonicator
· USP 8 Stage Dissolution Test Apparatus – LAB INDIA, Mumbai, India.
· USP 8 Stage Dissolution Test Apparatus - Electrolab, India.
· Disintegration Test Apparatus – Electrolab, India
· Multipurpose equipment

PROJECTS CARRIED OUT:

1. Formulation and optimization of gastro retentive floating drug delivery system of Cefuroxime axetil by BOX BEHNKEN method.
2. Formulation and evaluation of extended release matrix tablets of Losartan potassium by using Response Surface Methodology (RSM).
3. Formulation and evaluation of Piroxicam gel for topical application.
4. Formulation development and evaluation of Fast Dissolving tablets of Lornoxicam.
5. Formulation and optimization of gastro retentive floating drug delivery system of Cephalexin by using BOX BEHNKEN method.
6. Design and evaluation of Doxophyllin sustained release tablets.
7. Formulation and evaluation of Pramipexole hydrochloride extended release tablets.
8. Formulation and evaluation of floating effervescent tablets using Captopril as a model drug.
9. Design and evaluation of Efavirenz Oral disintegrating tablets.
10. Formulation and evaluation of Oxybutynin chloride extended release matrix tablets.
11. Development and in vitro evaluation of fast dissolving mucoadhesivebuccal disc of Domiperidone by using RSM optimal design.
12. Formulation and in vitro evaluation of Pantaprozole sodium muco adhesive tablets.
13. Formulation and evaluation of transdermal patches of Ondonsetron hydrochloride.
14. Development of extended release matrix tablets of Tramadol hydrochloride using Response Surface Methodology.
15. Design and evaluation of pH and time dependent compression coated Salbutamol sulphate tablets for the treatment of nocturnal asthma.
16. Formulation, optimization and evaluation of controlled release matrix tablets of Carvidilol using Response Surface Methodology.
17. Formulation and evaluation of TapentalolHCl extended release tablets.
18. Formulation and evaluation of Oral disintegrating tablets of piroxicam.
19. Formulation and evaluation of Oral disintegrating tablets of Ropinirole.

List of publications

1. Ravi Prakash P, Soujanya, Lakshmi Satya B, Lokesh Reddy M, Manogna K andRamesh A. Formulation and In vitro &In vivo evaluation of transdermal patches of Lornoxicam using natural permeation enhancers, Int J of Pharm and Pharm Sci. 2014;6(4) : 282-286.

2.Dastagiri Reddy Y,Dhachinamoorthi D, Chandra Sekhar KB. Preparation and characterization of Sucralfate suspension containing different suspending agents for improving suspendability. Int J Res Pharm Sci. 2014,(2), 1-5.

3.Dastagiri Reddy Y,Dhachinamoorthi D, Chandra Sekhar K B. Estimation of pharmacokinetic parameters and safety study of 5-flouracil drug loaded in sucralfate suspension, Medisinikarevija medical review, Dec 2014 Volume 6(3): 211-218.

4.Dastagiri Reddy Y,Dhachinamoorthi D, Chandra Sekhar K B.Formulation and in vitro evaluation of antineoplastic drug loaded nanoparticles as drug delivery system ,African Journal of Pharmacy and Pharmacology22 June, 2013, Vol. 7(23), 1592-1604.

5.Ravindrababu M and Sampathkumar K, Formulation and absorption enhancement of metformin tablets, Indo Amer J of Pharm Res.2013; 3 (10): 8273-79.

6. SaikatSen, Raja Chakraborty, Ravi Prakash Pand Sridhar C. Anti-inflammatory, analgesic, and antioxidant activities of Pisoniaaculeata: Folk medicinal use to scientific approach. PharmBio. 2013; Early Online: 1–7.

7. Ravi Sankar V, DastagiriReddy Y, Hanumantha Reddy G, Sudheer KumarReddy G. Formulation and Invitro Characterisation of sustained release Metronidazole -Cocoa ButterSuppositories. Inventi Impact: Pharm Tech, 2012; (4):275-280.

8. Ravi Sankar V, DastagiriReddy Y, Selva Kumar R. Conception and Evaluation of Theophylline Bi Layered Floating Tablets ;Inventi Rapid: NDDS,2010; 1(3).

9. Ravi Prakash P, Raghavendra Rao N G andSoujanya C. Formulation, evaluation and anti-inflammatory activity of topical etoricoxib gel, Asian J of Pharm and Cli Res. April-June 2010; 3 (2): 126 – 129.

10. Yagnesh Bhatt, AnandDeshmukh, Maulesh Joshi, SuhasNalle andRaviprakashPaladi. Evaluation and characterization of dispersible etoricoxib tablets, Int J Ph Sci. Sept-December 2009;1(2) p. 310-314.

11. NalleSuhas, MallikarjunaSetty C, Ravi Prakash P, Deepak Ghongade and Yagnesh Bhatt. Design and evaluation of controlled release nateglinide tablets using hydrophilic polymer, The Bioscan2009; 4 (1): 53 – 57.

12. Chowdary, K.P.R. and Ravi Prakash, P. Dissolution kinetics of meloxicam-?- cyclodextrin complex system, Int J Chem Sci. 2006; 4(4): p. 845-848.

13. RaghavendraRao,NG, Gupta V RM, Mutalik,S, Joshi V G andRavi Prakash P. Permeation of chlorzoxazone from gel formulations through mice skin. The Antiseptic, Apr.2005,102(4), 190-191.

14. Rambhimaiah S, Suresh D K, Gupta V R M, Bheemachari, Ravi Prakash Pand Srinivasa Rao P, Influence of metronidazole on the hypoglycaemic effect of tolbutamide in healthy albino rabbits, Indian Drugs. Sep. 2003, 40(9):535-538.

15. Ravi Sankar. V, Dachinamoorthi D and Chandra Shekar KB, A Comparative Pharmacokinetic study of Aspirin Suppositories and Aspirin Nanoparticles Loaded Suppositories, Clinic Pharmacol Biopharm 2012, 1:3. http://dx.doi.org/10.4172/2167-065X.1000105.

16. Ravi Sankar. V, Dachinamoorthi D, Chandra Shekar K.B Formulation and in vitro investigation of aspirin nanoparticles loaded supposi-tories as a drug delivery system for colorectal carcinoma. Int. J. Res. Pharm. Sci., 4(2), 1-11.

17. Ravi Sankar V, Dachinamoorthi D, Chandra Shekar K.B, Formulation and evaluation of novel Aspirin nanoparticles loaded suppositories, JCPS-2012-11-187.

18. V. Ravi Sankar, Y Dastagiri Reddy, G Sudheer Kumar Reddy, G Hanumantha Reddy, Formulation and In-vitro Characterisation of Regiospecific Floating Tablets of Stavudine, Inventi Rapid: NDDS Vol. 2012, Issue 4.

19. V. Ravi Sankar, Y.Dastagiri Reddy, K.Bhaskar, N. Vijaya Bhasakar, Formulation and Evaluation of Isabgol Based Matrix Tablets of Domperidone, Inventi Rapid: NDDS Vol. 2, Issue 1.

20. V. Ravi sankar, Y. Dastagiri Reddy, A. Nageswara rao, Dr. D.Dhachinamoorthy, Dr. K.B Chandra sekhar, Effect of Hydrophylic and Hydrophobic Polymers on Losartan Potassium matrix tablet, Journal of Pharmacy Research 2010, 3(9),2195-2197.

21. Ravi Sankar.V, Dastagiri Reddy.Y, T.S.Sreejit, J.Kausalya, and K. Bhaskar, Conception and evaluation of tramadol hydrochloride as extended release drug delivery system, Journal of Pharmacy Research 2010, 3(9), 2220-2222.

22. V. Ravi Sankar, Y Dastagiri Reddy, G Hanumantha Reddy, Formulation and evaluation of nimesulide based Hydrogel for topical application, Inventi Rapid: NDDS Vol. 2013, Issue 2.

23. Ravi Sankar. V, Dachinamoorthi D and Chandra Shekar KB, Pharmaco kinetic safety study of aspirin and aspirin nanoparticles loaded suppositories. Inventi Rapid: Pharmacokinetics & Pharmacodynamics Vol. 2013(3).

24. V. Ravi Sankar, Y. Dastagiri Reddy, NANOCOCHLEATE – A NEW APPROCH IN LIPID DRUG DELIVERY, Int J Pharm Pharm Sci, Vol 2, Issue 4, 220-223.

25. V. Ravi Sankar, Y. Dastagiri Reddy, N. Vijaya Bhaskar, Audi Naryana, N. Prathyusha, Sophia, Iontophoresis- A New Generation Approch Throug Transdermal Route, Inventi Rapid: Pharm Tech, 2011, Vol. 2, Issue 1.

26. V. Ravi sankar, Y. Dastagiri Reddy, A. Nageswara rao, Dr. D.Dhachinamoorthy, Dr. K.B Chandra sekhar, Chronotherapeutics :An Art of Dosage Form Designing, Journal of Pharmacy Research 2010, 3(7),1690-1696.

27. N. Vijaya Bhaskar,V. Ravi Sankar, Y. Dastagiri Reddy, V. Nagesh, Dr. C. Sridhar, A Brief About Trandermal Drug Delivery System, Journal of Pharmacy Research 2010, 3(11),2663-2673.

SEMINARS ATTENDED BY FACULTY

1. Y.Dastagiri Reddy 20-06-2011 to 24-06-2011 Brindavan Institute of Technology & Sciences, Kurnool, Teaching metadologies by National Institute of Technological Teachers Training & Research(NITTR), Chennai.
2. Ramanji Reddy & V.Ravisankar, 18-09-2010 to 19-09-2010, Brindavan Institute of Technology & Sciences, Teaching &Councelling skills. By Kasinathan, Pondicherry, Abhirani Academy.
3. Mr. V.Ravisankar & Mr.M.RavindraBabu, 22-01-2013 to 23-01-2013 J.S.S. College of Pharmacy, Mysore, Symposium on DOE and QBD (Quality by Design)
4. Mr.V.Ravisankar, 15-11-2013 to 17-11-2013 6th AASP Conference 2013 organized by AASP National University of Singapore. Singapore